Number theory is a branch of pure mathematics devoted primarily to the study of the integers and arithmetic functions. German mathematician Carl Friedrich Gauss (1777–1855) said, "Mathematics is the queen of the sciences—and number theory is the queen of mathematics." Number theorists study prime numbers as well as the properties of mathematical objects constructed from integers (for example, rational numbers), or defined as generalizations of the integers (for example, algebraic integers).

Integers can be considered either in themselves or as solutions to equations (Diophantine geometry). Questions in number theory can often be understood through the study of analytical objects, such as the Riemann zeta function, that encode properties of the integers, primes or other number-theoretic objects in some fashion (analytic number theory). One may also study real numbers in relation to rational numbers, as for instance how irrational numbers can be approximated by fractions (Diophantine approximation).

The older term for number theory is arithmetic, although this word today is used by the general public to mean elementary calculations. By the early twentieth century, the term number theory had been widely adopted. However, arithmetical is still commonly preferred as an adjective to number-theoretic.